Cleo Kontoravdi : rechercher sur Z-Library

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1

Amino acid and glucose metabolism in fed-batch CHO cell culture affects antibody production and glycosylation

Fan, Yuzhou, Jimenez Del Val, Ioscani, Müller, Christian, Wagtberg Sen, Jette, Rasmussen, Søren Kofoed, Kontoravdi, Cleo, Weilguny, Dietmar, Andersen, Mikael Rørdam

Journal:

Biotechnology and Bioengineering

Année:

2015

Langue:

english

Fichier:

PDF, 956 KB

english, 2015

2

Towards the implementation of quality by design to the production of therapeutic monoclonal antibodies with desired glycosylation patterns

Ioscani Jimenez del Val, Cleo Kontoravdi, Judit M. Nagy

Journal:

Biotechnology Progress

Année:

2010

Langue:

english

Fichier:

PDF, 823 KB

english, 2010

3

[Methods in Molecular Biology] Synthetic Biology Volume 1073 || Overlap Extension PCR Cloning

Polizzi, Karen M., Kontoravdi, Cleo

Année:

2013

Langue:

english

Fichier:

PDF, 367 KB

english, 2013

4

Techno-Economic Assessment of Cell-Free Synthesis of Monoclonal Antibodies Using CHO Cell Extracts

Thaore, Vaishali, Tsourapas, Dimitrios, Shah, Nilay, Kontoravdi, Cleo

Journal:

Année:

2020

Fichier:

PDF, 1.22 MB

2020

5

A dynamic mathematical model for monoclonal antibody N-linked glycosylation and nucleotide sugar donor transport within a maturing Golgi apparatus

Ioscani Jimenez del Val, Judit M. Nagy, Cleo Kontoravdi

Journal:

Biotechnology Progress

Année:

2011

Langue:

english

Fichier:

PDF, 1.07 MB

english, 2011

6

‘Closing the loop’ in biological systems modeling — From the in silico to the in vitro

Alexandros Kiparissides, Michalis Koutinas, Cleo Kontoravdi, Athanasios Mantalaris, Efstratios N. Pistikopoulos

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 806 KB

english, 2011

7

Development of a dynamic model of monoclonal antibody production and glycosylation for product quality monitoring

Cleo Kontoravdi, Steven P. Asprey, Efstratios N. Pistikopoulos, Athanasios Mantalaris

Journal:

Computers & Chemical Engineering

Année:

2007

Langue:

english

Fichier:

PDF, 571 KB

english, 2007

8

Systematic development of predictive mathematical models for animal cell cultures

Cleo Kontoravdi, Efstratios N. Pistikopoulos, Athanasios Mantalaris

Journal:

Computers & Chemical Engineering

Année:

2010

Langue:

english

Fichier:

PDF, 769 KB

english, 2010

9

Modeling Amino Acid Metabolism in Mammalian Cells-Toward the Development of a Model Library

Cleo Kontoravdi, Danny Wong, Carolyn Lam, Yih Yean Lee, Miranda G. S. Yap, Efstratios N. Pistikopoulos, Athanasios Mantalaris

Journal:

Biotechnology Progress

Année:

2007

Langue:

english

Fichier:

PDF, 214 KB

english, 2007

10

Analysis of Chinese hamster ovary cell metabolism through a combined computational and experimental approach

Chen, Ning, Bennett, Mark H., Kontoravdi, Cleo

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 735 KB

english, 2014

11

A multi-pronged investigation into the effect of glucose starvation and culture duration on fed-batch CHO cell culture

Fan, Yuzhou, Del Val, Ioscani Jimenez, Müller, Christian, Lund, Anne Mathilde, Sen, Jette Wagtberg, Rasmussen, Søren Kofoed, Kontoravdi, Cleo, Baycin-Hizal, Deniz, Betenbaugh, Michael J., Weilguny, Di

Journal:

Biotechnology and Bioengineering

Année:

2015

Langue:

english

Fichier:

PDF, 2.03 MB

english, 2015

12

Understanding the impact of different bioprocess conditions on monoclonal antibody glycosylation in CHO cell cultures through experimental and computational analyses

Sou, Si N, Sellick, Christopher, Lee, Ken, Mason, Alison, Kyriakopoulos, Sarantos, Polizzi, Karen M, Kontoravdi, Cleo

Journal:

BMC Proceedings

Année:

2015

Langue:

english

Fichier:

PDF, 1.26 MB

english, 2015

13

A model-based quantification of the impact of new manufacturing technologies on developing country vaccine supply chain performance: a Kenyan case study

Kis, Zoltán, Papathanasiou, Maria, Calvo-Serrano, Raul, Kontoravdi, Cleo, Shah, Nilay

Journal:

Journal of Advanced Manufacturing and Processing

Année:

2019

Langue:

english

Fichier:

PDF, 2.15 MB

english, 2019

14

Quantification of intracellular nucleotide sugars and formulation of a mathematical model for prediction of their metabolism

Ioscani Jiménez del Val, Judit M Nagy, Cleo Kontoravdi

Journal:

BMC Proceedings

Année:

2011

Langue:

english

Fichier:

PDF, 238 KB

english, 2011

15

Application of Global Sensitivity Analysis to Determine Goals for Design of Experiments: An Example Study on Antibody-Producing Cell Cultures

Cleo Kontoravdi, Steven P. Asprey, Efstratios N. Pistikopoulos, Athanasios Mantalaris

Journal:

Biotechnology Progress

Année:

2005

Langue:

english

Fichier:

PDF, 181 KB

english, 2005

16

Genome-based kinetic modeling of cytosolic glucose metabolism in industrially relevant cell lines:Saccharomyces cerevisiaeand Chinese hamster ovary cells

Chen, Ning, Koumpouras, Georgios C., Polizzi, Karen M., Kontoravdi, Cleo

Journal:

Bioprocess and Biosystems Engineering

Année:

2012

Langue:

english

Fichier:

PDF, 480 KB

english, 2012

17

Metabolic network reconstruction: advances in in silico interpretation of analytical information

Ning Chen, Ioscani Jimenez del Val, Sarantos Kyriakopoulos, Karen M Polizzi, Cleo Kontoravdi

Journal:

Current Opinion in Biotechnology

Année:

2012

Langue:

english

Fichier:

PDF, 350 KB

english, 2012

18

Analysis of the landscape of biologically-derived pharmaceuticals in Europe: Dominant production systems, molecule types on the rise and approval trends

Kyriakopoulos, Sarantos, Kontoravdi, Cleo

Journal:

European Journal of Pharmaceutical Sciences

Année:

2013

Langue:

english

Fichier:

PDF, 1.62 MB

english, 2013

19

A systems biology approach to optimising hosts for industrial protein production

Kate Royle, Cleo Kontoravdi

Journal:

Biotechnology Letters

Année:

2013

Langue:

english

Fichier:

PDF, 531 KB

english, 2013

20

[Methods in Molecular Biology] Synthetic Biology Volume 1073 || In Vivo and In Vitro Characterization of σ 70 Constitutive Promoters by Real-Time PCR and Fluorescent Measurements

Polizzi, Karen M., Kontoravdi, Cleo

Année:

2013

Langue:

english

Fichier:

PDF, 350 KB

english, 2013

21

[Methods in Molecular Biology] Synthetic Biology Volume 1073 ||

Polizzi, Karen M., Kontoravdi, Cleo

Année:

2013

Langue:

english

Fichier:

PDF, 6.18 MB

english, 2013

22

[Methods in Molecular Biology] Synthetic Biology Volume 1073 || What Is Synthetic Biology?

Polizzi, Karen M., Kontoravdi, Cleo

Année:

2013

Langue:

english

Fichier:

PDF, 111 KB

english, 2013

23

[Methods in Molecular Biology] Synthetic Biology Volume 1073 || Gene Synthesis Method Based on Overlap Extension PCR and DNAWorks Program

Polizzi, Karen M., Kontoravdi, Cleo

Année:

2013

Langue:

english

Fichier:

PDF, 144 KB

english, 2013

24

[Methods in Molecular Biology] Synthetic Biology Volume 1073 || Shuffling of DNA Cassettes in a Synthetic Integron

Polizzi, Karen M., Kontoravdi, Cleo

Année:

2013

Langue:

english

Fichier:

PDF, 77 KB

english, 2013

25

[Methods in Molecular Biology] Synthetic Biology Volume 1073 || Construction of Synthetic Gene Circuits in the Escherichia coli Genome

Polizzi, Karen M., Kontoravdi, Cleo

Année:

2013

Langue:

english

Fichier:

PDF, 202 KB

english, 2013

26

Comparative analysis of amino acid metabolism and transport in CHO variants with different levels of productivity

Kyriakopoulos, Sarantos, Polizzi, Karen M., Kontoravdi, Cleo

Journal:

Journal of Biotechnology

Année:

2013

Langue:

english

Fichier:

PDF, 2.12 MB

english, 2013

27

[Methods in Molecular Biology] Synthetic Biology Volume 1073 || In Vivo Screening of Artificial Small RNAs for Silencing Endogenous Genes in Escherichia coli

Polizzi, Karen M., Kontoravdi, Cleo

Année:

2013

Langue:

english

Fichier:

PDF, 394 KB

english, 2013

28

[Methods in Molecular Biology] Synthetic Biology Volume 1073 || Construction and Engineering of Large Biochemical Pathways via DNA Assembler

Polizzi, Karen M., Kontoravdi, Cleo

Année:

2013

Langue:

english

Fichier:

PDF, 506 KB

english, 2013

29

Dynamic profiling of amino acid transport and metabolism in Chinese hamster ovary cell culture

Kyriakopoulos, Sarantos, Polizzi, Karen M, Kontoravdi, Cleo

Journal:

BMC Proceedings

Année:

2013

Langue:

english

Fichier:

PDF, 344 KB

english, 2013

30

A quantitative and mechanistic model for monoclonal antibody glycosylation as a function of nutrient availability during cell culture

Jiménez del Val, Ioscani, Constantinou, Antony, Dell, Anne, Haslam, Stuart, Polizzi, Karen M, Kontoravdi, Cleo

Journal:

BMC Proceedings

Année:

2013

Langue:

english

Fichier:

PDF, 231 KB

english, 2013

31

An optimized method for extraction and quantification of nucleotides and nucleotide sugars from mammalian cells

del Val, Ioscani Jimenez, Kyriakopoulos, Sarantos, Polizzi, Karen M., Kontoravdi, Cleo

Journal:

Analytical Biochemistry

Année:

2013

Langue:

english

Fichier:

PDF, 1.19 MB

english, 2013

32

Development and design of bio-pharmaceutical processes

Kontoravdi, Cleo, Samsatli, Nouri J, Shah, Nilay

Journal:

Current Opinion in Chemical Engineering

Année:

2013

Langue:

english

Fichier:

PDF, 533 KB

english, 2013

33

Integration of models and experimentation to optimise the production of potential biotherapeutics

Royle, Kate E., Jimenez del Val, Ioscani, Kontoravdi, Cleo

Journal:

Drug Discovery Today

Année:

2013

Langue:

english

Fichier:

PDF, 581 KB

english, 2013

34

Analysis of the profile of unfolded protein response (UPR) markers in model-systems of Alzheimer's disease

Stefani, Ioanna, Kontoravdi, Cleo, Polizzi, Karen

Journal:

Alzheimer's & Dementia

Année:

2013

Langue:

english

Fichier:

PDF, 263 KB

english, 2013

35

Global sensitivity analysis and meta-modeling of an ethanol production process

Todri, Efti, Amenaghawon, Andrew N., del Val, Ioscani Jimenez, Leak, David J., Kontoravdi, Cleo, Kucherenko, Sergei, Shah, Nilay

Journal:

Chemical Engineering Science

Année:

2014

Langue:

english

Fichier:

PDF, 2.84 MB

english, 2014

36

Metabolic characterization and modeling of fermentation process of an engineered Geobacillus thermoglucosidasius strain for bioethanol production with gas stripping

Niu, Hongxing, Leak, David, Shah, Nilay, Kontoravdi, Cleo

Journal:

Chemical Engineering Science

Année:

2015

Langue:

english

Fichier:

PDF, 923 KB

english, 2015

37

Genetically-encoded biosensors for monitoring cellular stress in bioprocessing

Polizzi, Karen M, Kontoravdi, Cleo

Journal:

Current Opinion in Biotechnology

Année:

2015

Langue:

english

Fichier:

PDF, 736 KB

english, 2015

38

A framework for the systematic design of fed-batch strategies in mammalian cell culture

Kyriakopoulos, Sarantos, Kontoravdi, Cleo

Journal:

Biotechnology and Bioengineering

Année:

2014

Langue:

english

Fichier:

PDF, 2.04 MB

english, 2014

39

How does mild hypothermia affect monoclonal antibody glycosylation?

Sou, Si Nga, Sellick, Christopher, Lee, Ken, Mason, Alison, Kyriakopoulos, Sarantos, Polizzi, Karen M., Kontoravdi, Cleo

Journal:

Biotechnology and Bioengineering

Année:

2015

Langue:

english

Fichier:

PDF, 1.34 MB

english, 2015

40

Insights on biomarkers from Chinese hamster ovary ‘omics’ studies

Kyriakopoulos, Sarantos, Kontoravdi, Cleo

Journal:

Pharmaceutical Bioprocessing

Année:

2014

Langue:

english

Fichier:

PDF, 974 KB

english, 2014

41

FIBS-enabled Noninvasive Metabolic Profiling

Behjousiar, Alireza, Constantinou, Antony, Polizzi, Karen M., Kontoravdi, Cleo

Journal:

Journal of Visualized Experiments

Année:

2014

Langue:

english

Fichier:

PDF, 321 KB

english, 2014

42

Towards Controlling the Glycoform: A Model Framework Linking Extracellular Metabolites to Antibody Glycosylation

Jedrzejewski, Philip, del Val, Ioscani, Constantinou, Antony, Dell, Anne, Haslam, Stuart, Polizzi, Karen, Kontoravdi, Cleo

Journal:

International Journal of Molecular Sciences

Année:

2014

Langue:

english

Fichier:

PDF, 1.08 MB

english, 2014

43

The Role of ER Stress-Induced Apoptosis in Neurodegeneration

C. Stefani, Ioanna, Wright, Daniel, M. Polizzi, Karen, Kontoravdi, Cleo

Journal:

Current Alzheimer Research

Année:

2012

Langue:

english

Fichier:

PDF, 502 KB

english, 2012

44

Modelling of amorphous cellulose depolymerisation by cellulases, parametric studies and optimisation

Niu, Hongxing, Shah, Nilay, Kontoravdi, Cleo

Journal:

Biochemical Engineering Journal

Année:

2016

Langue:

english

Fichier:

PDF, 6.60 MB

english, 2016

45

Designing an Artificial Golgi reactor to achieve targeted glycosylation of monoclonal antibodies

Klymenko, Oleksiy V., Shah, Nilay, Kontoravdi, Cleo, Royle, Kate E., Polizzi, Karen M.

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 1.01 MB

english, 2016

46

Model-based investigation of intracellular processes determining antibody Fc-glycosylation under mild hypothermia

Sou, Si Nga, Jedrzejewski, Philip M., Lee, Ken, Sellick, Christopher, Polizzi, Karen M., Kontoravdi, Cleo

Journal:

Biotechnology and Bioengineering

Année:

2016

Langue:

english

Fichier:

PDF, 2.76 MB

english, 2016

47

A theoretical estimate for nucleotide sugar demand towards Chinese Hamster Ovary cellular glycosylation

del Val, Ioscani Jimenez, Polizzi, Karen M., Kontoravdi, Cleo

Journal:

Scientific Reports

Année:

2016

Langue:

english

Fichier:

PDF, 1.89 MB

english, 2016

48

In Situ Monitoring of Intracellular Glucose and Glutamine in CHO Cell Culture

Behjousiar, Alireza, Kontoravdi, Cleo, Polizzi, Karen M., Coles, Jonathan A.

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 390 KB

english, 2012

49

Whole-cell Escherichia coli lactate biosensor for monitoring mammalian cell cultures during biopharmaceutical production

Goers, Lisa, Ainsworth, Catherine, Goey, Cher Hui, Kontoravdi, Cleo, Freemont, Paul S., Polizzi, Karen M.

Journal:

Biotechnology and Bioengineering

Année:

2017

Langue:

english

Fichier:

PDF, 1.38 MB

english, 2017

50

An improved model framework linking the extracellular environment to antibody glycosylation

Philip M Jedrzejewski,Karen M Polizzi,Cleo Kontoravdi

Journal:

BMC Proceedings

Année:

2015

Langue:

english

Fichier:

PDF, 572 KB

english, 2015